Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL
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چکیده
منابع مشابه
Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL
Zeta-associated protein of 70 kD (ZAP70) is a recognized adverse prognostic marker in chronic lymphocytic leukaemia (CLL) associated with enhanced B-cell receptor signalling, significantly more aggressive disease course and poor overall survival. Zeta-associated protein of 70 kD is ordinarily expressed in T cells where it has a crucial role in T-cell receptor signalling, whereas its aberrant ex...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2012
ISSN: 1582-1838
DOI: 10.1111/j.1582-4934.2011.01503.x